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Immunol., 2005; 117:38-46.

Induction of interferon-gamma from natural killer cells by immunostimulatory CpG DNA is mediated through plasmacytoid-dendritic-cell-produced interferon-alpha and tumor necrosis factor-alpha.

Jason D. Marshall, Darren S. Heeke, Christi Abbate, Priscilla Yee and Gary Van Nest.


Science, 1996; 273: 352-354.

Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization.

Sato, Y., M. Roman, H. Tighe, D. Lee, M. Corr, M.D. Nguyen, G.J. Silverman, M. Lotz, D.A. Carson, and E. Raz.


Nature Medicine, 1997; 3: 849-854.

Immunostimulatory DNA Sequences Function as T helper-1-promoting Adjuvants.

Roman, M., E. Martin-Orozco, J.S. Goodman, M.D. Nguyen, Y. Sato, A. Ronaghy, R.S. Kornbluth, D.D. Richman, D.A. Carson, and E. Raz.


Cell. Immunol., 1998; 190: 77-82.

Immunostimulatory DNA Is a Potent Mucosal Adjuvant.

Horner, A.A., A. Ronaghy, P.M. Cheng, M.D. Nguyen, H.J. Cho, D. Broide, and E. Raz.


J. Virol., 2002; 76: 11387-11396.

Use of Immunostimulatory Sequence-Containing Oligonucleotides as Topical Therapy for Genital Herpes Simplex Virus Type 2 Infection.

Pyles, R.B., D. Higgins, C. Chalk, A. Zalar, J. Eiden, C. Brown, G. Van Nest, and L.R. Stanberry.


J. Leukoc. Biol., 2003; 73(6):781-792.

Identification of a novel CpG DNA class and motif that optimally stimulate B cell and plasmacytoid dendritic cell functions.

Marshall, J.D., K. Fearon, C. Abbate, S. Subramanian, P. Yee, J. Gregorio, R.L. Coffman, and G. Van Nest.


Eur. J. Immunol., 2003; 33: 2114-2122.

A minimal human immunostimulatory CpG motif that potently induces IFN-gamma and IFN-alpha production.

Fearon, K., J.D. Marshall, C. Abbate, S. Subramanian, P. Yee, J. Gregorio, G. Teshima, G. Ott, S. Tuck, G. Van Nest, and R.L. Coffman.


Nucl. Acids Res., 2003; 31(17):5122-5133.

Novel chimeric immunomodulatory compounds containing short CpG oligodeoxyribonucleotides have differential activities in human cells.

Marshall, J.D., E.M. Hessel, J. Gregorio, C. Abbate, P. Yee, M. Chu, G.V. Nest, R.L. Coffman, and K.L. Fearon.


Blood, 2003; 102(13):4487-4492.

IL-10 regulates plasmacytoid dendritic cell response to CpG-containing immunostimulatory sequences.

Duramad, O., K.L. Fearon, J.H. Chan, H. Kanzler, J.D. Marshall, R.L. Coffman, and F.J. Barrat.


J. Immunol., 2004; 173(3):1647-1657.

CpG-C immunostimulatory oligodeoxyribonucleotide activation of plasmacytoid dendritic cells in rhesus macaques to augment the activation of IFN-gamma-secreting simian immunodeficiency virus-specific T cells.

Teleshova, N., J. Kenney, J. Jones, J. Marshall, G. Van Nest, J. Dufour, R. Bohm, J.D. Lifson, A. Gettie, and M. Pope.