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01/06/2015

DNA Cell Biol., 2005; 24(2):63-72.

Superior Activity of the Type C Class of ISS In Vitro and In Vivo Across Multiple Species.

Marshall, J.D., K.L. Fearon, D. Higgins, E.M. Hessel, H. Kanzler, C. Abbate, P. Yee, J. Gregorio, T.D. Cruz, J.O. Lizcano, A. Zolotorev, H.M. McClure, K.M. Brasky, K.K. Murthy, R.L. Coffman, and G.V. Nest.

01/06/2015

Immunity, 2005; 23:465-478.

Human TLR-7-, -8-, and -9-Mediated Induction of IFN-alpha/beta and -lambda is IRAK-4 Dependent and Redundant for Protective Immunity to Viruses.

Kun Yang, Anne Puel, Shenying Zhang, Céline Eidenschenk, Cheng-Lung Ku, Armanda Casrouge, Capucine Picard, Horst von Bernuth, Brigitte Senechal, Sabine Plancoulaine, Sami Al-Hajjar, Abdulaziz Al-Ghonaium, László Maródi, Donald Davidson, David Speert, Chaim Roifman, Ben-Zion Garty, Adrian Ozinsky, Franck J. Barrat, Robert L. Coffman, Richard L. Miller, Xiaoxia Li, Pierre Lebon, Carlos Rodriguez-Gallego, Helen Chapel, Frédéric Geissmann, Emmanuelle Jouanguy, and Jean-Laurent Casanova.

01/06/2015

J. Exp. Med., 2006; 203(8):1999-2008.

Properties Regulating the Nature of the Plasmacytoid Dendritic Cell Response to TLR9 Activation.

Cristiana Guiducci, Gary Ott, Jean H. Chan, Emily Damon, Carlo Calacsan, Tracy Matray, Kyung-Dall Lee, Robert L. Coffman and Franck J. Barrat.

01/06/2015

Immunity, 2006; 25:665-664.

Toll-like Receptor Recognition Regulates Immunodominance in an Antimicrobial CD4+ T Cell Response.

Felix Yarovinsky, Holger Kanzler, Sara Hieny, Robert L. Coffman, and Alan Sher.

01/06/2015

J. Clin. Invest., 2009; 119(9):2564–2576.

CpG-containing immunostimulatory DNA sequences elicit TNF-α–dependent toxicity in rodents but not in humans.

John D. Campbell, Yan Cho, Martyn L. Foster, Holger Kanzler, Melissa A. Kachura, Jeremy A. Lum, Marianne J. Ratcliffe, Atul Sathe, Andrew J. Leishman, Ash Bahl, Mark McHale, Robert L. Coffman and Edith M. Hessel.

01/06/2015

Immunity, 2011; 34(3):375-384.

Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response.

Hou B, Saudan P, Ott G, Wheeler ML, Ji M, Kuzmich L, Lee LM, Coffman RL, Bachmann MF, DeFranco AL.

01/06/2015

J. Immunol., 2005; 174:5193–5200.

Inhibitors of TLR-9 Act on Multiple Cell Subsets in Mouse and Man In Vitro and Prevent Death In Vivo from Systemic Inflammation.

Omar Duramad, Karen L. Fearon, Bonnie Chang, Jean H. Chan, Josh Gregorio, Robert L. Coffman, and Franck J. Barrat.

01/06/2015

J. Exp. Med., 2005; 202(8):1131-1139.

Nucelic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus.

Franck J. Barrat, Thea Meeker, Josh Gregorio, Jean H. Chan, Satoshi Uematsu, Shizuo Akira, Bonnie Chang, Omar Duramad, and Robert L. Coffman.

01/06/2015

Journal of Leukocyte Biology, 2007; 82(3):497-508.

Negative regulation of TLR9-mediated IFN-{alpha} induction by a small-molecule, synthetic TLR7 ligand.

Marshall JD, Heeke DS, Gesner ML, Livingston B, Van Nest G.

01/06/2015

Blood, 2007; 110:2907-2915.

Interferon-{alpha} promotes abnormal vasculogenesis in lupus: a potential pathway for premature atherosclerosis.

Denny M.F., Thacker S., Mehta H., Somers E.C., Dodick T., Barrat F.J., McCune W.J. and Kaplan M.J.