Ongoing Studies

New vaccines that potentially help protect people are only possible because of volunteers who participate in clinical research. Joining a clinical trial is an important decision that should be discussed with a healthcare provider. 

DV2-TDAP-01 

Overview
A Phase 1 randomized, participant-blinded, active-controlled, dose escalation, clinical trial to evaluate the safety, tolerability, and immunogenicity of an investigational tetanus/diphtheria/pertussis (Tdap) booster vaccine utilizing CpG 1018 adjuvant compared to a licensed Tdap vaccine in healthy volunteers between 10 and 22 years of age. The trial is being conducted in Australia.

Title: A study to evaluate the safety and tolerability of Tetanus/Diphtheria/Pertussis Booster Vaccine compared to a licensed Tdap vaccine in Healthy Volunteers between 10 - 22 years of age

Status: Ongoing

Anzctr.org.au Identifier: ACTRN12620001177943p

These molecules and their uses are investigational, have not been proven to be safe, and have not been approved by the U.S. Food and Drug Administration or by any health authority

DV2-ZOS-01

Overview
A Phase 1 randomized, active-controlled, dose-escalation, clinical trial to evaluate the safety, tolerability, and immunogenicity of investigational herpes zoster (shingles) vaccine utilizing CpG 1018 adjuvant compared to Shingrix^® in healthy volunteers between the ages of 50 and 69 years of age. 

Title: A Phase 1 Randomized, Subject-Blinded, Active-Controlled, Dose Escalation, Multicenter Trial to Evaluate the Safety, Tolerability, and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix^® in Healthy Adult Volunteers Between the Ages of 50 and 69 Years.

Status: Recruiting

ClinicalTrials.gov NCT Identifier: NCT05245838

These molecules and their uses are investigational, have not been proven to be safe, and have not been approved by the U.S. Food and Drug Administration or by any health authority.

DV2-HBV-27 (Pregnancy Registry)

The HEPLISAV-B pregnancy registry is an observational study being conducted in the United States to evaluate pregnancy outcomes in women vaccinated with HEPLISAV-B^® within 28 days prior to conception or at any time during pregnancy. The purpose of the registry is to learn more about the health of infants born to mothers exposed to HEPLISAV-B^® during pregnancy. The registry is sponsored by Dynavax Technologies and PPD, Inc.

Title: HEPLISAV-B^® Pregnancy Registry: an observational study on the safety of HEPLISAV-B exposure in pregnant women and their offspring

Status: Recruiting

Learn more: HEPLISAV-B Pregnancy Registry

Contact Information

Toll-free number: 1-844-443-7734

Email: heplisavbpregnancyregistry@ppdi.com

ClinicalTrials.gov NCT Identifier: NCT03664648